#022 Understanding my desire to be a biotech entrepreneur | Mauritz Venter
16 July 2022 · 24 min · as at 2022-07-16
Petro du Pisani (host) · Mauritz Venter (guest)
Listen to the episode on iono.fm · MP3
About the guest
Mauritz Venter
CEO and co-founder · AzarGen Biotechnologies
A scientist by training who studied human genetics and started a biotech startup at the end of his post-grad studies. He completed the Executive MBA at UCT's Graduate School of Business, researching his desire to be a biotech entrepreneur.
In Mauritz's own words:
“I'm a, I'm a scientist, by training. I started studying human genetics pre-grad, and, I was always intrigued during those years when I studied, intrigued by the business of, of science, business of specifically biotechnology,”
“at the end of my post-grad studies, I, I started a biotech venture, a biotech startup, and, during that time, You know, doing science as well in the lab and also writing business plans and pitching to investors and raising, money and all the entrepreneurial startup, stuff that you do during the valley of, that they call the startup valley of death.”
“I've done these business courses at various business schools, but, two courses I did at UCT GSB, Finance for Non-Financial Managers, and the other one was a Project Management course,”
Guest details come from the published episode notes or the guest's own words in the episode.
Episode analysis
Analysis by AI, drawn only from this episode; every point links to the moment it rests on.
Petro du Pisani interviews fellow UCT GSB Executive MBA student Mauritz Venter, a scientist and biotech founder, about his research project on his desire to be a biotech entrepreneur. Mauritz explains how a strategy assignment prompted the question of why he stays in a high-risk venture despite oscillating passion and fear of failure. He describes the practical rationality methodology based on breakdowns and sense-making, the themes his auto-hermeneutic study produced, and how he unified them into 'the performative manifestation of being'. The host adds her own reflections on reflective practice, phenomenology and values as a filter for future choices.
Key ideas
- Mauritz frames his research around why an entrepreneur sustains action when passion and fear of failure keep oscillating, calling the constant thread 'desire'. [04:59]▸ [06:18]▸ [06:27]▸
- Mauritz explains practical rationality: while absorbed in practice, a breakdown, unintended or deliberate, triggers reflection through which sense-making happens. [08:19]▸ [09:09]▸ [09:20]▸ [09:45]▸
- Mauritz found that love for science, rather than the entrepreneurial journey itself, underlies his desire, since academic and entrepreneurial projects produced the same feelings. [13:27]▸ [13:36]▸
- Mauritz reports that telling stakeholders and family during a breakdown, rather than holding it in, relieved tension, which he names relational connectedness. [12:52]▸ [12:52]▸
- Mauritz argues the themes cannot be seen in isolation; their interrelatedness forms a global theme applicable to any practice seeking a desired outcome. [16:07]▸ [16:25]▸ [16:52]▸ [17:20]▸
- Mauritz defines desire as actions taken in response to a projection of what is imagined, a purposeful, goal-directed way of being. [20:37]▸ [21:29]▸
- The host argues that knowing your values acts as a filter for choosing direction; without knowing your purpose, choosing is very difficult. [19:46]▸ [19:47]▸
Practical rationality (breakdown and sense-making)
- Be absorbed and immersed in the flow of a practice, taking tools and surroundings for granted.
- Experience a temporary interruption or breakdown, either unintended or a deliberate intervention.
- Stop for a moment and reflect on your entwinement with others and things.
- Through that reflection sense-making happens and you grasp the logic of your practice.
As described in the episode: [08:19]▸ [09:09]▸ [09:45]▸ [10:21]▸
Lessons
- Mauritz suggests that sharing a setback with stakeholders and family, rather than withdrawing, can relieve tension during a breakdown. [12:52]▸
- Mauritz advises continuous reflection and not taking things for granted, which he says brings appreciation and gratefulness. [18:53]▸ [19:00]▸
- Mauritz argues that repeatedly reflecting on your actions through your own values confirms whether something is worthwhile and brings you close to truthfulness. [22:30]▸ [22:42]▸
- Mauritz's experience indicates that examining what drives you can reveal a different motivation than assumed, such as love for science over entrepreneurship. [13:27]▸
- Petro suggests clarifying your purpose so it can serve as a filter for deciding where to spend future time. [19:46]▸
Who it's for
Science-trained founders, biotech entrepreneurs and professionals considering an Executive MBA, especially those interested in reflective practice, phenomenological research and understanding what sustains them through risk and uncertainty.
Facts stated in the episode
- Petro says Mauritz won the class award for the research project that most embodied the spirit of the MBA philosophy. [00:40]▸
- Mauritz took Finance for Non-Financial Managers and a Project Management course at UCT GSB. [02:16]▸
- His research title includes 'Finding Orientation with Growth, Meaning, and Resilience'. [06:06]▸
- The practical rationality framework draws on philosopher Martin Heidegger's concept of entwinement. [10:21]▸
- Mauritz used a modified autobiographical method called auto-hermeneutics. [11:05]▸
- His global theme was named 'The performative manifestation of being'. [16:52]▸
Questions this episode answers
- Why would a scientist choose to do an Executive MBA?Mauritz says he had specialised in science and needed business expertise; the UCT EMBA appealed because it is implemented in practice on real business data rather than memorised to get a mark. [01:02]▸ [02:46]▸
- What keeps an entrepreneur going despite fear of failure?Mauritz calls it desire, a constant line through the oscillation between passion and fear of failure, which his study linked to love for science, relational connectedness, willingness and aesthetic appreciation. [06:18]▸ [12:18]▸ [13:27]▸ [13:42]▸
- What is practical rationality as a research method?Mauritz describes it as grasping the logic of your practice through breakdowns: interruptions in the flow of work that prompt reflection and sense-making, drawing on Heidegger's idea of entwinement. [08:19]▸ [08:19]▸ [09:09]▸ [10:21]▸
- What is auto-hermeneutics?Mauritz explains it as a modified autobiographical method: the study and interpretation of his own autobiographical narrative, used within phenomenology. [11:05]▸
- How should you handle a setback in a startup?Mauritz found that telling his stakeholders and family during a breakdown, instead of holding it in, relieved the tension. [12:52]▸ [12:52]▸
- How does Mauritz define desire?As actions taken in response to a projection of what is imagined, the potentiality of what could be, and a purposeful, goal-directed way of being to act, think and feel towards something you want. [20:37]▸ [21:29]▸
- Do the findings apply beyond entrepreneurship?Mauritz says that after unifying his themes into 'the performative manifestation of being', he saw it applied to any practice where you seek a desired outcome. [16:52]▸ [17:20]▸
- What did the EMBA change in how Mauritz thinks?He says he now reflects continuously, tries not to take things for granted, and infuses findings with his own values and character. [18:00]▸ [18:53]▸
In their own words
Longer stretches of the conversation, word for word from the transcript, turn by turn.
From human genetics to biotech startup and EMBA
Note (AI): Mauritz's own account of his scientific training, founding a biotech startup, short business courses and why the practice-based EMBA appealed to him.
Mauritz Venter, guest · [01:02]I'm a, I'm a scientist, by training. I started studying human genetics pre-grad, and, I was always intrigued during those years when I studied, intrigued by the business of, of science, business of specifically biotechnology, and its major in-influence from the, from the US, from activities in the US, mapping the human genome and companies like that. So I, I decided this is something that I want to pursue, that …
Read the full passage (333 words, 01:02–03:08)
Mauritz Venter, guest · [01:02]I'm a, I'm a scientist, by training. I started studying human genetics pre-grad, and, I was always intrigued during those years when I studied, intrigued by the business of, of science, business of specifically biotechnology, and its major in-influence from the, from the US, from activities in the US, mapping the human genome and companies like that. So I, I decided this is something that I want to pursue, that I want to be in and be involved with, especially with this almost love for science that I'm, that I, that I realize I, I have. And, and yeah, so I, after, at the end of my post-grad studies, I, I started a biotech venture, a biotech startup, and, during that time, You know, doing science as well in the lab and also writing business plans and pitching to investors and raising, money and all the entrepreneurial startup, stuff that you do during the valley of, that they call the startup valley of death. You know, I, I, I've done quite a few short business courses that I thought, look, I've, I've specialized in, in science, but I really need some business expertise, and I've done these business courses at various business schools, but, two courses I did at UCT GSB, Finance for Non-Financial Managers, and the other one was a Project Management course, and, it was during that time that, I heard about the, the Executive MBA course, and I thought, this is very intriguing, you know, something different, and it was only ten years later that, yeah, I, I went to an information session on this course, so when they highlighted the idea that this is not just Information that you memorize and regurgitate to get a mark, this is something that you implement in practice. This is something that, that you really, it's real life, real data that, that they evaluate you on, in your business. I thought this is fascinating and yeah, I decided let's, let's go for it.
How the research topic on desire emerged
Note (AI): Explains how a strategy assignment led to studying desire and why resilience between passion and fear of failure mattered.
Mauritz Venter, guest · [04:59]Yes, that actually, it came out of a, a concept or phenomenon that I was intrigued with during our strategy block. The topic came out of a, a strategy assignment, and within this assignment, I, I focused while I was developing the, this, this, while we developed a theory of strategy, this whole idea of actions that are, that need to be taken in, in, to achieve a desired outcome …
Read the full passage (335 words, 04:59–06:50)
Mauritz Venter, guest · [04:59]Yes, that actually, it came out of a, a concept or phenomenon that I was intrigued with during our strategy block. The topic came out of a, a strategy assignment, and within this assignment, I, I focused while I was developing the, this, this, while we developed a theory of strategy, this whole idea of actions that are, that need to be taken in, in, to achieve a desired outcome or maintain a desired state in business. And this word desire, it was sort of, you know, I, I was intrigued by that because it's something that you want to achieve, but what is this? What is this desire? And I was drawn to this, to, you know, to this concept. So my theme for my, you know, I decided to take that out of, out of the strategy paper and, and, and, yeah, go further with that. And that was the, I wanted to know what this, I called it the clarity of desire. And, and how do you gain clarity of this desire? What is this desire? And, Yeah, it started there, Petro. It started out of that, and that was... I took a chance actually with this topic, and luckily the, the lecturers and, you know, they accepted this. Obviously, I had to add my whole bioentrepreneurial practice to this topic, the... And I've, I've added to the title, Finding Orientation with Growth, Meaning, and Resilience. And the resilience part was actually the important part because that came out of real... my real life experience, is why do you still stay in the game? How can you sustain entrepreneurial action if this oscillation between passion and fear of, fear of failure is consistently there? You know, what, what is it? And I called it the desire. it's, it's as if it was this constant line going through these oscillations of passion and fear of failure. And yeah, that's the topic that I thought, okay, this is what I want to take forward.
Practical rationality: breakdowns and sense-making explained
Note (AI): A step-by-step explanation of the research framework: immersion in practice, breakdown, reflection and sense-making, grounded in Heidegger.
Mauritz Venter, guest · [08:19]I, I used a research methodology that was proposed by my, my supervisor. it was, it's called practical rationality. And it's actually a great concept. The idea is, and it's, it's, the idea is while you are in the flow of practice, and, we've, we've done, we've done now the, the idea of what is a practice, and strategies practice, leadership as practice, but actually anything that you are involved …
Read the full passage (401 words, 08:19–10:45)
Mauritz Venter, guest · [08:19]I, I used a research methodology that was proposed by my, my supervisor. it was, it's called practical rationality. And it's actually a great concept. The idea is, and it's, it's, the idea is while you are in the flow of practice, and, we've, we've done, we've done now the, the idea of what is a practice, and strategies practice, leadership as practice, but actually anything that you are involved with, any activity that you, while you are busy with others, other people or things you take for granted, you are absorbed in it, you are immersed in it, you don't focus too much on necessarily on, let's say, I'm working on the laptop or this, here's my desk, all of this, these things. You don't f- you know, this is taken almost for granted, but there might be a temporary disruption or interruption, and they, the theory for practical rationality is, you can grasp the logic of your practice. Once you experience this interruption, they call it a breakdown. And it's in response to this breakdown where sense-making happens. And all that is actually that is, is a reflection. You stop for a moment, it's temporary. You stop, reflect on it. And it happens in business, it happens in with a, with a project that you are busy with. it can happen with anything that you are busy in the flow of what you are doing, and suddenly it stops. There's an interruption. And this, this interruption can be, something unin- unintended, unexpected. It can be a massive thing in business that happened, or it can be deliberate. It can be a deliberate intervention, that you decided, oh, no, I, I'm busy with this project or busy with this activity, but I'm, I'm deliberately stopping this. And due to that small interruption and you reflecting on that, The idea, the, the logic of this theoretical framework is, or the, the idea of the theoretical framework is, it's there where you make now sense of your environment, and it's based on the philosopher Martin Heidegger of his philosophy of, we are always in, he calls it entwinement, we are always entwined with others and things, and you are absorbed in that, and once there's a breakdown, sense-making happens while you are reflecting on that entwinement, and that is how you then grasp the logic of your practice. That was the framework.
The themes behind sustaining entrepreneurial desire
Note (AI): Lists the study's findings, including the surprise that love for science, not entrepreneurship, drives him, and the role of telling others during breakdowns.
Mauritz Venter, guest · [12:18]So the, the major themes in response to, to the breakdowns using my theoretical framework were willingness, willingness to accept what unfolds, willingness to, to be rooted in reality, significance and credibility, that was a theme. I would call it, I called it strategic management and leadership potential, but actually that is skillful coping, that was a, a theme that came out. very, some of them were quite surprising to …
Read the full passage (336 words, 12:18–14:25)
Mauritz Venter, guest · [12:18]So the, the major themes in response to, to the breakdowns using my theoretical framework were willingness, willingness to accept what unfolds, willingness to, to be rooted in reality, significance and credibility, that was a theme. I would call it, I called it strategic management and leadership potential, but actually that is skillful coping, that was a, a theme that came out. very, some of them were quite surprising to me, relational connectedness. I found that during a breakdown, instead of holding it, you know, and, and go, almost going into a depression and, and, you know, not telling anyone, I told everyone. I, I told my stakeholders, I told my family, I, so I found that, that, that relieved the tension. So that was relational connectedness. Another one was emotional sensory and bodily expression. I, I didn't realize how powerful, that, that theme was in, in, in sustaining bio, biological action. The other one was love, love for, for science. I thought when I started out was love for the bio-entrepreneurial journey, the action, the stress, the excitement, the com- the combination of all those things, but it wasn't. It was actually the love for science. I had the same feelings when doing an academic project versus an entrepreneurial project. And then the last one that was the most surprising one to, to me, but it had, had mo- had almost the most basic themes to support it, was aesthetic and linguistic appreciation. The idea of something that is beautiful, something, something with, with beauty, leading, be leading beautifully. The beauty of the, the, the modern biotech lab, the, the, the articles that I read, you know, from, from business, from magazines that highlight, biotech companies in the US, just the linguistic piece there, the articulation of it, that, that sense of excitement when I read it, the photos of those labs of the, you know, the, the, the science, that was quite a s- something that, that was sig- significant of, of these findings.
Unifying themes into the performative manifestation of being
Note (AI): Shows how Mauritz links the themes into one global theme and argues it applies to any practice seeking a desired outcome.
Mauritz Venter, guest · [16:07]It's actually a difficult one because I'm, I'm, I sat with the same type of, you know, what you've mentioned now, you're in a mining industry, and then how do these things, you know, translate to that? And I sat with that same challenge, you know, in, in how do these concepts now relate to that? And so maybe a longer, long answer now to this question is, is also …
Read the full passage (225 words, 16:07–17:29)
Mauritz Venter, guest · [16:07]It's actually a difficult one because I'm, I'm, I sat with the same type of, you know, what you've mentioned now, you're in a mining industry, and then how do these things, you know, translate to that? And I sat with that same challenge, you know, in, in how do these concepts now relate to that? And so maybe a longer, long answer now to this question is, is also you cannot see these things in isolation. And to apply that was I need to look at the linkages. I need to look at the interrelatedness of these themes. And then out of that, they were unified into a global theme, because that's the only way I could, I could really orientate myself, to see that what, so what, answering that question, what does all of this mean? And I called it The performative manifestation of being. That's the major theme that came out of this, that, you know, symbolizes the active experience of my, what I'm going on inside of, with the ongoing search for, for this character development, and also fostering this clarity of, of by action and continuous reflection, which seems to sustain desire in a high-risk entrepreneurial endeavor. So, so through that, I thought it was not only for entrepreneurship, it was to any practice where you seek a desired outcome.
Quotes
“this is not just Information that you memorize and regurgitate to get a mark, this is something that you implement in practice.”
“How can you sustain entrepreneurial action if this oscillation between passion and fear of, fear of failure is consistently there?”
“And it's in response to this breakdown where sense-making happens.”
“I found that during a breakdown, instead of holding it, you know, and, and go, almost going into a depression and, and, you know, not telling anyone, I told everyone.”
“It was actually the love for science. I had the same feelings when doing an academic project versus an entrepreneurial project.”
“I thought it was not only for entrepreneurship, it was to any practice where you seek a desired outcome.”
“be a bit more aware of what are you really busy with, and out of that comes appreciation and gratefulness.”
“it's like a filter, that you can then go, okay, well, this, this either resonates with me or it doesn't, or it aligns with my purpose or it doesn't.”
“I think this is the closest you can get to, get to truthfulness, to, to get what is, what truth means to you.”
What was said, by topic
Biotech entrepreneurship
“I'm a, I'm a scientist, by training. I started studying human genetics pre-grad, and, I was always intrigued during those years when I studied, intrigued by the business of, of science, business of specifically biotechnology,”
“at the end of my post-grad studies, I, I started a biotech venture, a biotech startup, and, during that time, You know, doing science as well in the lab and also writing business plans and pitching to investors and raising, money and all the entrepreneurial startup, stuff that you do during the valley of, that they call the startup valley of death.”
“I thought when I started out was love for the bio-entrepreneurial journey, the action, the stress, the excitement, the com- the combination of all those things, but it wasn't. It was actually the love for science. I had the same feelings when doing an academic project versus an entrepreneurial project.”
Executive MBA learning
“He is the person in our class who won the award for the research project that most embodied the spirit of the MBA philosophy.”
“I've done these business courses at various business schools, but, two courses I did at UCT GSB, Finance for Non-Financial Managers, and the other one was a Project Management course,”
“when they highlighted the idea that this is not just Information that you memorize and regurgitate to get a mark, this is something that you implement in practice.”
“But I would say the psychology, the mindfulness, the philosophy, that part of this whole course, that played a immense role in, in my, my development of, I would say the overall development of, of the self, as I, or, or being.”
“I also found the position papers we wrote in every block or every course, you know, that the, from a practical perspective, just applying that immediately back into your workplace. And that helped me to grow and also eventually get promoted, I guess, or, or find a new job halfway through,”
Desire and resilience
“The topic came out of a, a strategy assignment, and within this assignment, I, I focused while I was developing the, this, this, while we developed a theory of strategy, this whole idea of actions that are, that need to be taken in, in, to achieve a desired outcome or maintain a desired state in business.”
“Obviously, I had to add my whole bioentrepreneurial practice to this topic, the... And I've, I've added to the title, Finding Orientation with Growth, Meaning, and Resilience.”
“And the resilience part was actually the important part because that came out of real... my real life experience, is why do you still stay in the game? How can you sustain entrepreneurial action if this oscillation between passion and fear of, fear of failure is consistently there?”
“So I knew the feeling, the felt sense, but I didn't know the, the, on the academic side, you know, what, what this would entail.”
“So the, the major themes in response to, to the breakdowns using my theoretical framework were willingness, willingness to accept what unfolds, willingness to, to be rooted in reality, significance and credibility, that was a theme.”
“I found that during a breakdown, instead of holding it, you know, and, and go, almost going into a depression and, and, you know, not telling anyone, I told everyone. I, I told my stakeholders, I told my family, I, so I found that, that, that relieved the tension.”
“And then the last one that was the most surprising one to, to me, but it had, had mo- had almost the most basic themes to support it, was aesthetic and linguistic appreciation. The idea of something that is beautiful, something, something with, with beauty, leading, be leading beautifully.”
“And I called it The performative manifestation of being. That's the major theme that came out of this, that, you know, symbolizes the active experience of my, what I'm going on inside of, with the ongoing search for, for this character development,”
“So, so through that, I thought it was not only for entrepreneurship, it was to any practice where you seek a desired outcome.”
“I came up with it as a, you know, as, as defined as the actions that are taken in response to a projection of what is imagined, the, the potentiality, because that served me well during my entrepreneurial, venture,”
“It's based on another ontology of becoming. It's a way of existence. It's a way of being to act, think, and feel towards something that you want, that you really, you know, that you feel with your whole being, this is something that I want, but in a certain purposeful, goal-directed way.”
Practical rationality research
“I used a research methodology that was proposed by my, my supervisor. it was, it's called practical rationality.”
“the theory for practical rationality is, you can grasp the logic of your practice. Once you experience this interruption, they call it a breakdown. And it's in response to this breakdown where sense-making happens.”
“And this, this interruption can be, something unin- unintended, unexpected. It can be a massive thing in business that happened, or it can be deliberate. It can be a deliberate intervention,”
“it's based on the philosopher Martin Heidegger of his philosophy of, we are always in, he calls it entwinement, we are always entwined with others and things,”
“I used an autobiographical method, but it was a modified autobiographical method called auto-hermeneutics. And all that means is it's the study, it's, it's the interpretation, it's the study of inter-interpreting my autobiographical narrative.”
“I think the thing I really appreciated about phenomenology is the beauty of it. It's such a beautiful research methodology because you're really trying to get to underlying meaning and what does a thing truly mean?”
Reflective practice
“is, is also you cannot see these things in isolation. And to apply that was I need to look at the linkages. I need to look at the interrelatedness of these themes.”
“any project that I, you know, want to do or things that I'm busy with, not to take things for granted, be a bit more aware of what are you really busy with, and out of that comes appreciation and gratefulness.”
Values and meaning
“You have to infuse that with your own values, with your own character and, and your, your development of yourself.”
“It's very, it's like a filter, that you can then go, okay, well, this, this either resonates with me or it doesn't, or it aligns with my purpose or it doesn't. But if you don't know what your purpose is, or, or at least what you're aspiring to become, then it's very difficult to choose a direction to go into the future.”
“you keep on reflecting on it by infusing your own values to, to, that, that keeps on confirming that this is something good, this is something worthwhile doing. I think this is the closest you can get to, get to truthfulness,”
Episode notes (as published)
From the episode notes published with the podcast.
A learning journey conversation with a fellow EMBA student. I recently completed an Executive MBA through the University of Cape Town's Graduate School of Business. With classes moving on-line (in 2020 and 2021) due to the covid-19 pandemic there wasn't enough time (for me) to connect with fellow students and hear about their research projects. I decided to interview my fellow students to learn about their research. In this podcast I speak to Dr. Mauritz Venter, CEO and co-founder of AzarGen Biotechnologies about his desire to be a biotech entrepreneur. Being an entrepreneur is risky, and Mauritz wanted to explore why even in spite of uncertainty, risk and anxiety there was nothing else he would rather do. This study followed on from the intense reflective practice which is part of the EMBA course. Delving deeper into his desire to be a biotech entrepreneur he found that this desire was a result of trying to be true to his values in finding a meaningful orientation that would lead to creating a better world. Learn more about UCT's EMBA � Connect with Dr. Mauritz Venter � Connect with Petro � Solid Gold Podcasts
Every quotation and passage on this page is copied word for word from the episode audio transcript and linked to the moment it was said. Quotations are never written or altered by AI; topic labels, passage notes and the episode analysis are AI-generated. Guest details come from the published episode notes or the guest's own words.
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